cannabisnews.com: NHS Patients To Be Given Cannabis NHS Patients To Be Given Cannabis Posted by CN Staff on August 20, 2003 at 15:01:17 PT Some patients will receive cannabis-based medicine Source: BBC News NHS patients are to be given cannabis as part of a government-funded trial. The study, which is being run by the Medical Research Council, aims to find out if the drug really can help to relieve pain. Scientists will randomly select 400 patients who have undergone surgery from 36 hospitals across the UK to take part in the study. They will be given one of four pills after undergoing surgery, two of which will be a form of cannabis. Controlled study They will receive a capsule containing standardised cannabis extract or a capsule containing tetrahydrocannabinol - the active ingredient in cannabis. Many patients and clinicians want an answer to the question of whether cannabis is effective at relieving pain. - Dr Anita Holdcroft, Imperial College LondonThe remaining patients will receive either a standard pain-relieving drug or a dummy pill. Researchers will ask the patients about their pain and general well-being at least once every hour while they are awake, over a six hour-period. The patients will be able to request additional pain relief at any time. The researchers will then be able to compare the experiences of patients in each of the four groups and, hopefully, determine whether the cannabis-based treatments are effective. The £500,000 trial is being headed by scientists at Imperial College London. "Many patients and clinicians want an answer to the question of whether cannabis is effective at relieving pain," said Dr Anita Holdcroft, who will lead the study. "We need to assess the scientific merits of some of the anecdotal evidence and we need to do this in the same way as any other experimental pain treatment. "This is a proper study in a clinical setting where patients can be routinely monitored, using an oral capsule containing a prescribed dose." Without it, I don't know what I would do. - Richard Spencer, Paralysed cannabis userStudies have suggested that cannabis and cannabis-based medicines can help to relieve pain. Richard Spencer, who was paralysed 23 years ago after breaking his legs, said using the drug as part of a medical trial took away his pain, relaxed spasms in his legs and allowed him to sleep. "Without it, I don't know what I would do," he told BBC Radio 4's Today programme. "I just wish it was available 20 years ago, I would have used it. Certainly, I would have had quality in my life." Last year, a small trial involving 34 British patients with multiple sclerosis, spinal cord injury and other conditions causing severe pain, found that using cannabis-based treatments reduced their pain and helped them to sleep more soundly. US approval Researchers have also found evidence to suggest it can help to reduce the side effects of chemotherapy treatment given to cancer patients. In the United States, the Food and Drug Administration has approved the oral use of dronabinol, a cannabis derivative, for people with Aids. There is evidence that cannabis may stimulate the appetites of Aids patients with wasting disease. It may also help relieve the pain of menstrual cramps and childbirth. Claims have also been made for its use in treating asthma, strokes, Parkinson's Disease, Alzheimer's Disease, alcoholism and insomnia. However, opponents of the use of cannabis point to the fact that it damages the ability to concentrate and, if smoked, may increase the risks of developing lung cancer. The British Medical Association has said that only cannabinoids - part of the cannabis plant - should be used in medicine. Frank Warburton, director of Drugscope, a charity that comments on drug-related policy, said: "The therapeutic benefits of cannabis have been well-known for some time. "We welcome this trial which appears to be a sensible and rational exploration of these benefits, and look forward to seeing the results of the evaluation." Q & A: Cannabis Pain Trial NHS patients are to be given cannabis-based drugs to see if it helps relieve pain. BBC News Online looks at what the research will involve. What will the research look at? Scientists will randomly select 400 patients who have undergone surgery from hospitals across the UK to take part in the study. They hope to discover if cannabis-based medicines can help ease post-operative pain. Each patient will be given one of four pills, two of which will be cannabis-based pills, one of which will be a painkiller with the other a dummy pills. Neither the patients nor the doctors will know who gets which pill. The patients will then be asked about their pain in the hours after their operations. The study, which is run by the Medical Research Council, is being funded by the government. Will the patients be smoking cannabis? No. One of the pills will be cannabinoids - the active constituents of cannabis. One will be a natural cannabinoid, the other tetrahydrocannabinol- a synthetic cannabinoid. Will the patients get high? No. The medication will only give patients the same kind of well-being they would get from other forms of pain-relief. Is there evidence cannabis can ease pain? Studies have indicated that cannabis-based drugs can ease post-operative pain, though some studies have indicated the medication is no more effective than codeine. Other studies have suggested that cannabinoids can ease chronic pain associated with conditions cancer and spinal cord injury. Tests of a cannabis-based spray have also been shown to help relieve multiple sclerosis symptoms. Many MS sufferers say smoking cannabis relieves their condition, but a number have been prosecuted for using the illegal drug. When could cannabis-based drugs for post-operative pain be available? There have already been trials to test if these drugs are safe. This trial is to test how effective they are. However, much more research is needed, and it could be some years before doctors can prescribe them for patients. Source: BBC News (UK Web) Published: Wednesday, August 20, 2003Copyright: 2003 BBC Contact: newsonline bbc.co.ukWebsite: http://news.bbc.co.uk/ Related Articles & Web Site:Medical Marijuana Information Linkshttp://freedomtoexhale.com/medical.htmCannabis Trials Are 'Delaying Tactic'http://cannabisnews.com/news/thread17114.shtmlCannabis on Trial for Pain Relief http://cannabisnews.com/news/thread17108.shtml Home Comment Email Register Recent Comments Help Comment #1 posted by afterburner on August 20, 2003 at 19:23:07 PT: Meanwhile, On This Side of the Ocean - Prop. S US CA: Pot And The People 20 Aug 2003 The San Francisco Bay Guardian http://www.mapinc.org/newscc/v03/n1249/a03.html?397 [ Post Comment ] Post Comment