cannabisnews.com: New Drug Takes You on a Bum Trip










  New Drug Takes You on a Bum Trip

Posted by CN Staff on August 31, 2002 at 10:57:27 PT
By Shane Holladay -- Staff Writer 
Source: Edmonton Sun 

Butt out those joints - a U.S. researcher is close to rolling out an alternative for medical marijuana exemptees that may put an end to their need for weed. Dr. Mahmoud ElSohly has developed a rectal suppository that delivers a therapeutic dose of THC - the active ingredient of marijuana - without the harmful effects of smoking and with one other twist, he says. 
 "You don't get that stoned feeling," said ElSohly, a University of Mississippi research professor who does U.S. government sponsored research of marijuana and other drugs. "It cuts down on that edge that you normally get with THC." Suppositories are the next more direct route to deliver THC into the bloodstream after smoking, he said. Rob, a medical marijuana exemptee living in Edmonton, said he's skeptical scientists can cut out the euphoric aspect of THC without cutting its effectiveness. "They seem to want to alter it when it's proven to be effective just the way it is," he said. The drug ElSohly patented in 1996 - dronabinol hemisuccunate (DHS) - is a precursor to THC. It is quickly absorbed into fatty tissues of the lower intestine. As DHS is gradually released into the bloodstream, it's chemically transformed into THC. Source: Edmonton Sun (CN AB) Author: Shane Holladay -- Staff WriterPublished: August 31, 2002 Copyright: 2002 Canoe Limited PartnershipContact: sun.letters ccinet.ab.ca Website: http://www.fyiedmonton.com/htdocs/edmsun.shtmlRelated Article:Researchers Aim To Develop Marijuana Without High http://cannabisnews.com/news/thread8835.shtmlCannabisNews Medical Marijuana Archiveshttp://cannabisnews.com/news/list/medical.shtml 

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Comment #15 posted by John Tyler on September 01, 2002 at 07:12:59 PT

1 term for Bush
Bush and his people have angered, disappointed, and annoyed, a lot of other people in many ways. In this month's issue of PC magazine John Devorak, a PC techno pundit predicted a one term presidency just because of his many failings with regard to the economy.  
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Comment #14 posted by qqqq on September 01, 2002 at 02:12:45 PT

...I hear You HerbDoc....
....EXODUS....Movement of JAH People...................
 
 
...."I have finally come to the realization that " they " are not going to see reason, relent or hear our sue for mercy so we
      must now start looking for some place that will give sactuary from Rome as it no longer enough being outcast.
 
 
.....BUT...the most hair-raising part of todays Empire of Amerika,,is that it is now legal to hunt down and kill or imprison dissenters...If you are not for the empire,,you are against it....you can be labeled an "enemy combatant", for saying something that kaiser ashcroft doesn't like.......and we all know what happens to "enemy combatants"; ..they drop off the face of the earth!.........you cannot escape from Rome!....as soon as Ceasar labels you as "al-queada" ,you will be tracked down by the empire,,whos' power trancends the globe!...Perhaps one will soon have to attempt to seek asylum in China!...(?)... 
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Comment #13 posted by Herbdoc215 on September 01, 2002 at 00:15:02 PT

We Must Demand Our Own Zionist Movement
I have finally come to the realization that " they " are not going to see reason, relent or hear our sue for mercy so we must now start looking for some place that will give sactuary from Rome as it no longer enough being outcast. We have bent over backwards and turned many cheeks to LEO's in our search for justice and freedom- both from physical pain and laws meant to cause spiritual pain. Our entire culture has been hunted into the ground the entire world over and replaced with a violent subculture of violence that we always retreated from instead of being confrontational. Look where that pacifist nature has been the very weapon that oppressive " MAJORITY POPULATIONS " has used against us. I say populations instead of governments because my year in Canada has illiterated the fact owe so well that governments really are representitive of the " MAJORITY " of the population in control of the infrastructure in any geographic location in world. We must look inside ourselves as a people and face the racial scio-economic nature of the drug laws and what we fear so bad we are willing to sacrifice our children in some "quasi" Aztec ritual killing. Is the world or humanity worth utterly destoying to save it for 'progress'? I refuse to believe my Grandfather layed on the beaches of Okanowi so his Grandson could be hunted down like a dog to be killed in a public show trial to let everyone know how mad somebody must be to stand against the United States of America's intrest! I sure wasn't expecting this little experience as a side effect of going into military instead of jail as a kid for getting caught growing pot. I sure wish now that I had just been a poor black child so I would have just been sent to jail and raped or stabbed instead of getting driven into ground, and then getting hounded into it by the same government? I guess cannabis can kill you, but only if you are born in the US. Peace, Steven Tuck       in exile
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Comment #12 posted by Herbdoc215 on August 31, 2002 at 23:50:33 PT

Would debating Himmler have saved 1 Jewish person?
 "You don't get that stoned feeling," said ElSohly, a University of Mississippi research professor who does U.S. government sponsored research of marijuana and other drugs. How do you debate a professional whore who has spent his entire career stealing other mens work and putting his name and spin upon it? Logic? Think that black hearted kitten raping, dog kicking, wife beating hack can keep lies straight enough to even keep on topic? I never heard a word he said that didn't sound like an infomercial. I could go on all night about just this one mans crimes. I would give anything get him and Ann " I wish she was HALF as uncomfortable as my back" McClellen in a room for JUST ONE MINUTE and I could die a happy man. Hate? maybe but if you were in my body now or understood what it felt like to go beg for something that you can grow as good as anyone else in the world because you dared try to help another or had THE TERMERITY to actually want to sleep through a night or play with your kids or even God forbid make love to your wife like a real man THEN you can tell me what it's like to be dying in a land far from anyone who cares and all alone. Sometimes I just wish this was all over and a bad,bad dream and I'll wake up and it will be in my own home? Steven Tuck
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Comment #11 posted by MDG on August 31, 2002 at 23:22:50 PT

The title really makes sense...
New Drug Takes You on a Bum Trip since that's where the meds are going.
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Comment #10 posted by pppp on August 31, 2002 at 22:56:19 PT

....that old song:..
"Dont bogart that suppository ,,my friend
 
Pass it on over to me.."
 
 
...If rectal medication is so great,,why dont they have Paxil,or Zoloft for your butt?....next thing ya know,, they'll be marketing booze for your ass....some kinda Zima douche,,or a Jack Daniels enema!
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Comment #8 posted by JR Bob Dobbs on August 31, 2002 at 21:58:12 PT

Insert your own anal joke here
How much is this slated to cost? And when will it be available? I bet it'll be a while before it comes to market - "Just suffer in the meantime or we'll lock you up!" - and it'll cost more than whole smoked cannabis, even if you're lucky enough to have insurance.
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Comment #7 posted by knox42897 on August 31, 2002 at 15:03:44 PT:

Stupid doctors
This is very upsetting to me. I have been a smoker for 15 years. These doctors are getting desperate to make money from this. But please nerve of these doctors, I think they do this crap on purpose.
Pierre
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Comment #6 posted by FoM on August 31, 2002 at 12:53:52 PT

Dr. Russo
The news is slow because it is a holiday weekend and I want to make sure you understand how wonderful you are. No, I don't want you to think you are wonderful or you would be conceited and then I wouldn't like you! LOL! All kidding a side thank you. My husband is very sick today and on days like this I get very upset when I see drugs that are suppose to take the place of a God given plant in the news.
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Comment #5 posted by Ethan Russo MD on August 31, 2002 at 12:41:38 PT:

Problems
Americans do not prefer suppositories. Reportedly they are more acceptable in Europe.Beyond that, this will never catch on. It is true that rectal administration avoids some of the conversion of THC to 11-hydroxy-THC that is a problem with Marinol orally, but the real difficulty is that cannabis is more than just THC! This preparation will have none of the synergistic cannabinoids and terpenoids of the natural preparations. Dr. ElSohly and I will be debating this point in the correspondence section of the journal Psychopharmacology, as they have provisionally accepted my LTE. See his group's article:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12073159&dopt=Abstract
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Comment #3 posted by lineman on August 31, 2002 at 11:43:41 PT

chem
Must not be very hard to convert this stuff to THC in your kitchen.
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Comment #2 posted by Sam Adams on August 31, 2002 at 11:42:07 PT

LIAR
"Suppositories are the next more direct route to deliver THC into the bloodstream after smoking, he said."No, the most direct route is vaporizing, then smoking, then probably an aerosal spray.It's sad now that most doctors are corporate pawns, instead of compassionate people that promote a healthy well-being and lifestyle for their patients. If the doctor still had to come to your house, or talked to you for more than 5 minutes at the office, they would never suggest this. Any doctor that tried to come to my house and make me use a suppository instead of my Aromazap would have to be bitch-slapped.
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Comment #1 posted by cplollie on August 31, 2002 at 11:31:06 PT

up yours
so the only way we can take this is to take it up the A-hole. is that what U.S. Government are saying. Well hell it should all be legal then we been taking it up there for a long time By the DEA and all the U.S. laws and the war on drugs.I'll tell them where they can stick it!!!
Cannabis jarhead
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