cannabisnews.com: Like Marijuana, Minus The Munchies Like Marijuana, Minus The Munchies Posted by FoM on November 08, 2001 at 07:13:19 PT By Mayrav Saar Source: Orange County Register UCI scientists discovered that a marijuana-like chemical suppresses the munchies, countering decades of informal research into a kindred compound by undergraduate students everywhere.UCI's research, conducted on laboratory rats, was published today in the journal Nature, and scientists hope the findings will lead to a treatment for obesity. The paper's co-author, University of California, Irvine, pharmacology professor Daniele Piomelli, said oleylethanolamide, or OEA, a naturally occurring molecule in the same family as marijuana's active ingredient, reduced appetite when injected into rats."The actual marijuana-like compound is a food stimulator," Piomelli said. "They come from the same class of compound but act in an opposite fashion."The next step, researchers said, is to test OEA in obese rats.Rats injected with the chemical did not get high or feel so much as a tingle in the cannabinoid receptors of their brains.But unlike other diet-suppressing compounds that can trigger agitation, the marijuana kin seemed to cause little worry for the furry subjects.At high doses, OEA had the same calming effect that its brethren chemical has been known to create in humans."We don't understand it fully," Piomelli said. "But if you crank up the dose, you see an inhibition of motor activity." Note: UCI study finds pot-like chemical suppresses appetite, may fight obesity. Source: Orange County Register (CA)Author: Mayrav SaarPublished: November 8, 2001Copyright: 2001 The Orange County RegisterContact: letters link.freedom.comWebsite: http://www.ocregister.com/Related Articles & Web Sites:Journal Naturehttp://www.nature.com/nature/Medical Marijuana Information Linkshttp://freedomtoexhale.com/medical.htmMarijuana Munchies May Hold a Key to Obesity http://cannabisnews.com/news/thread9340.shtmlStraight Dope on the Munchies http://cannabisnews.com/news/thread9338.shtmlMarijuana-Like Substance in Brain Trigger Appetite http://cannabisnews.com/news/thread9337.shtml END SNIP --> Snipped Home Comment Email Register Recent Comments Help Comment #4 posted by FoM on November 08, 2001 at 09:38:38 PT Thank You Dr. Russo I was trying to think of something witty to call you but I can't think of anything. I'll blame it on old age, stml or brain fog. Hey, they are good excuses sometimes! LOL! [ Post Comment ] Comment #3 posted by Ethan Russo MD on November 08, 2001 at 07:27:11 PT: Thanks, FoM You're a peach, and I want everyone to know! [ Post Comment ] Comment #2 posted by FoM on November 08, 2001 at 07:25:43 PT Dr. Russo Here's the direct link and I will add it to my medical site today! You are doing such a great job and I really appreciate you. It's so nice to have a Doctor in the house who knows about Cannabis. http://www.cannabis-med.org/science-international/JCANT.htm [ Post Comment ] Comment #1 posted by Ethan Russo MD on November 08, 2001 at 07:18:15 PT: Off Topic Promotion I would like to announce that the entire contents of the Journal of Cannabis Therapeutics 1(1) Charter Issue are now available free online:http://www.cannabis-med.org/english/home.htmScroll down and push the Journal of Cannabis Therapeutics link.While you are visiting, please consider joining the IACM (International Association for Cannabis as Medicine). In so doing, you will be supporting a vital organization and will receive a JCANT subscription as part of membership. [ Post Comment ] Post Comment